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Minimum time for maximum efficiency

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Software version available

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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A clinical trial is being designed to evaluate the efficacy of an intermediate-acting niacin preparation in a population with regard to amelioration of coronary artery disease risk.
Bioethical considerations would restrict recruitment of subjects with poorly controlled diabetes mellitus, recent gastroduodenal ulcer disease, or hyperuricemia. Which principle would consider these patients to be ineligible for enrollment?

A) Justice
B) Beneficence
C) Autonomy
D) Equipoise

2. A 25-year-old man with type 1 diabetes mellitus has recorded the following average blood - glucose concentrations for the past 5 days:

Which of the following changes in his insulin regimen is most appropriate?

A) Increase the morning NPH insulin.
B) Increase the evening regular insulin.
C) Increase the evening NPH insulin.
D) Decrease the morning regular insulin.

3. Which of the following components of a grant proposal defines the study hypothesis?

A) Specific aims
B) Significance
C) Background
D) Research design

4. A 46-year-old patient begins treatment with allopurinol 300 mg daily following the onset of an acute gout attack due to elevated uric acid.
The patient's other medications are:
* Cyclosporine 800 mg daily
* Prednisone 20 mg daily
* Azathioprine 100 mg daily
* Nifedipine extended release 90 mg daily
Several days later there was an observed decrease in the patient's WBC count. Which drug interaction with allopurinol is most likely to account for this change?

A) Prednisone
B) Cyclosporine
C) Nifedipine
D) Azathioprine

5. A 67-year-old patient is hospitalized for decompensated heart failure. The serum sodium concentration is 130 mEq/L on admission. Which of the following is the most appropriate approach to managing the patient's hyponatremia?

A) Restriction of both sodium and fluids
B) 3% NaCl 50 mL/h intravenously for 5 hours
C) 0.9% NaCl 200 mL/h intravenously for 5 hours
D) Conivaptan 20 mg intravenously over 24 hours

Solutions: